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May 17
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A myIBSteam Member

Thank you!

May 17
myIBSteam

Great news that the pain is improving β€” that's a real win! But diarrhea after every meal sounds exhausting, and it's a very common experience when starting Linzess (linaclotide), especially in the first few weeks.

Linzess works by pulling water into the intestines to help things move along β€” which is great for IBS-C, but Show Full Answer

Great news that the pain is improving β€” that's a real win! But diarrhea after every meal sounds exhausting, and it's a very common experience when starting Linzess (linaclotide), especially in the first few weeks.

Linzess works by pulling water into the intestines to help things move along β€” which is great for IBS-C, but can sometimes work a little *too* well at first. Here are a few things worth knowing and trying:

- Timing matters β€” Taking Linzess on an empty stomach, at least 30 minutes before your first meal of the day, is the recommended approach and may help manage urgency
- Give it time β€” For many people, the diarrhea side effect settles down after the first few weeks as the body adjusts
- Stay hydrated β€” Diarrhea can cause fluid loss, so keeping water intake up is important
- Talk to your doctor β€” If it remains severe, your doctor may adjust your dose. Don't stop taking it without checking first

Since it's only been 4 days, it may be worth hanging in there a little longer while staying in close contact with your healthcare provider about what you're experiencing.

May 17

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