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List of Treatments for IBS

See what members are saying about IBS treatments, the side effects to expect, and the drug basics.

All treatment information is medically reviewed · November 6, 2025

Amitiza (Lubiprostone)

Overview
Amitiza is a prescription medication approved by the Food and Drug Administration (FDA) treat chronic constipation in women 18 and older who have irritable bowel syndrome (IBS). Amitiza is also known by its drug…

Bentyl (Dicyclomine)

Overview
Bentyl is a prescription medication approved by the Food and Drug Administration (FDA) treat irritable bowel syndrome (IBS). Bentyl is also known by its drug name, Dicyclomine
Bentyl is an anticholinergic…

Colestid (Colestipol)

Overview
Colestid is a prescription medication approved by the Food and Drug Administration (FDA) to lower blood serum cholesterol. Colestid may be prescribed off-label in cases of irritable bowel syndrome (IBS) to treat…

IB-Stim

Overview
The IB-Stim is a device approved by the U.S. Food and Drug Administration (FDA) for people between the ages of 11 and 18 for the management of abdominal pain from irritable bowel syndrome (IBS). The IB-Stim is…

Ibsrela (Tenapanor)

Overview
Ibsrela is approved by the U.S. Food and Drug Administration (FDA) for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults. It should not be used in children younger than 18 years old…

Imodium (Loperamide)

Overview
Imodium is an over-the-counter product intended to control the symptoms of diarrhea. Imodium is also known by its drug name, Loperamide
Imodium is an antidiarrheal. It is believed that Imodium works by…

Kaopectate (Bismuth subsalicylate)

Overview
Kaopectate is an over-the-counter product intended to control the symptoms of diarrhea. Kaopectate is also known by its drug name, Bismuth subsalicylate
Kaopectate is an antacid and antidiarrheal. It is…

Levsin (Hyoscyamine)

Overview
Levsin is a prescription medication approved by the Food and Drug Administration (FDA) treat irritable bowel syndrome (IBS) in conjunction with other drugs. Levsin is also known by its drug name, Hyoscyamine…

Linzess (Linaclotide)

Overview
Linzess is approved by the U.S. Food and Drug Administration (FDA) for the treatment of irritable bowel syndrome with constipation (IBS-C) in adults and in children aged 7 and up. Linzess should not be used in…

Lomotil (Diphenoxylate/Atropine)

Overview
Lomotil is approved by the Food and Drug Administration (FDA) as an adjunctive therapy for the treatment of diarrhea. Lomotil is a combination of the drugs Diphenoxylate and Atropine
Diphenoxylate is an opioid…

Lotronex (Alosetron)

Overview
Lotronex is approved by the Food and Drug Administration (FDA) to treat severe diarrhea-predominant irritable bowel syndrome (IBS) in women. Lotronex may be prescribed in cases where IBS has lasted at least six…

Pepto-Bismol (Bismuth subsalicylate)

Overview
Pepto-Bismol is an over-the-counter product intended to control the symptoms of diarrhea. Pepto-Bismol is also known by its drug name, Bismuth subsalicylate
Pepto-Bismol is an antacid and antidiarrheal. It is…

Psychotherapy

Overview
Irritable bowel syndrome (IBS) is frequently associated with psychological factors such as stress, anxiety, and depression. Emotional distress can cause worsening of symptoms in many people with IBS…

Valium (Diazepam)

Overview
Valium is a prescription drug approved by the Food and Drug Administration (FDA) to treat anxiety. Valium is also known by its drug name, Diazepam
Valium is an anxiolytic (antianxiety medication) of the…

Viberzi (Eluxadoline)

Overview
Viberzi is approved by the Food and Drug Administration (FDA) to treat irritable bowel syndrome (IBS) with diarrhea. Viberzi is also referred to by its drug name, Eluxadoline
Viberzi is an antidiarrheal…

Xifaxan (Rifaximin)

Overview
Xifaxan is approved by the Food and Drug Administration (FDA) to treat diarrhea-predominant irritable bowel syndrome (IBS-D) in adults. Xifaxan is also referred to by its drug name, Rifaximin
Xifaxan is an…

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