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Dicyclomine. I've had IBS for over 30 years and was never told about any drugs that could help ease the pain of gas, bloating and cramping until 5 months ago when I saw a Gastrointestinal Doc. He gave me this and it helps me not to be in so much pain. I still have diarrhea but at least I'm not in such severe pain. Also if you have upper GI pain, I've found Famatodine 20mg to be very helpful.