I get horrible nausea along with pain and bloating. Also muscle and joint pain in my back, shoulders and knees. I can go for months with manageable symptoms, and then out of nowhere, I'm down and out for days. I forgot to add the sweats are awful too.

I have IBS-C. I'm on Linzess, which worked in begining now have to take with Miralax. The up's n downs are too much. Either have hard pain in stomach, feels like a bowling ball or in the bathroom constantly. I want IBS gone or would like to know where it came from.

OMG, I clicked the up thumb to nearly all of them. Got one to add: huge bleeding hemorrhoids! I, too, get the constipation first, painful cramping and chills, and then diarrhea. BUT guys! I have found one solution for the painful cramping=dicyclomine in 10 or 20 mgs. It halts the cramping at least so I can sleep. It has helped me so much. I start out with a 10 mg (20 mgs cut in half) and rarely have had to go to 20 mgs.

Constant stomach pain. Runny diarrhea which goes right through me. I have ruined many underwear.

Probably the fatigue after a flare up. Takes a day or so to recover.