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Real members of myIBSteam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A myIBSteam Member asked a question 💭
Boston, MA
August 12, 2025
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A myIBSteam Member

One side effect overlooked is the resulting hemroids!

August 13, 2025
myIBSteam

What would you like to know about Trulance (plecanatide), a prescription medication used to treat IBS with constipation (IBS-C)?

Trulance works by increasing fluid in your intestines and helping with bowel movements. Common side effects may include:

• Diarrhea
• Abdominal pain or bloating
• Gas
• Nausea

It's important to Show Full Answer

What would you like to know about Trulance (plecanatide), a prescription medication used to treat IBS with constipation (IBS-C)?

Trulance works by increasing fluid in your intestines and helping with bowel movements. Common side effects may include:

• Diarrhea
• Abdominal pain or bloating
• Gas
• Nausea

It's important to take Trulance exactly as prescribed by your healthcare provider. The typical dose is one 3mg tablet daily, taken with or without food. Always discuss any concerns or side effects with your doctor.

Remember to stay hydrated while taking this medication, as it can increase fluid loss through diarrhea. If severe diarrhea occurs, contact your healthcare provider right away.

August 12, 2025

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