Try creatine. It has been found to relieve constipation.
June 11
Can Cymbalta make IBS-related constipation worse? That's a really important question worth exploring with a doctor.
Cymbalta (duloxetine) is sometimes prescribed for IBS due to its effect on gut-brain nerve signaling. However, constipation is a known side effect of this type of medication, so it's possible it could worsen Show Full Answer
Can Cymbalta make IBS-related constipation worse? That's a really important question worth exploring with a doctor.
Cymbalta (duloxetine) is sometimes prescribed for IBS due to its effect on gut-brain nerve signaling. However, constipation is a known side effect of this type of medication, so it's possible it could worsen IBS-C symptoms for some people.
If constipation is becoming a concern, there are some options that may help manage it alongside any medication:
- Fiber supplements like Metamucil (psyllium) taken with plenty of water
- Osmotic laxatives such as polyethylene glycol or magnesium hydroxide
- Staying well hydrated throughout the day
- Gentle exercise within a comfortable range
It's really worth having an open conversation with a doctor or gastroenterologist about whether Cymbalta is the right fit, or if the dose needs adjusting. They can help weigh the benefits against any worsening gut symptoms.
Other myIBSteam members have shared their own experiences managing constipation — it might be comforting to know others are navigating similar challenges!
June 10